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Induction of genetic competence of S. mutans strains in response to UA159sp or TPC3. The strains used included SMCC3 (comC), which was unable to produce but still respond to UA159sp; SMEK-1 (comE), which did not respond to UA159sp at all; and JH1005, which had a peptide (TPC3) of the C-terminal truncation. S. mutans UA159 was used as a positive control, while mutant SMEK-1 (comE) was used as a negative control.
