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Effects of LSA and RALP mutation on resistance to whole blood and antimicrobial peptide killing. (A) Survival of WT M1 GAS and isogenic ΔLSA and ΔRALP3 mutants in fresh human whole blood; (B) killing of WT M1 GAS and isogenic ΔLSA and ΔRALP3 mutants by the murine cathelicidin antimicrobial peptide mCRAMP (28 μM).
