FIG. 6.

Binding of CovR to PdppA binding site mutant DNA. Shown is DNase I protection of wild-type PdppA (335-bp fragment) and each consensus binding site mutant DNA (CB-1* through CB-5*). Panel A shows the binding of CovR to binding site mutant DNA CB-1*, CB-2*, and CB-3* (sense strand), while panel B shows the binding of CovR to CB-4* and CB-5* DNA (antisense strand). Regions of protection are indicated by solid lines, and the location of each mutation (TT-to-GG substitution) is indicated to the right of each footprint by a large asterisk. The images are cropped to show the relevant data.