TABLE 1.
Patient characteristics for 32 study subjects
Study subject | Count (cells/mm3)
|
Log10 plasma viral load (copies/ml) | Stagea | Estimated duration of infectionb (days) | |
---|---|---|---|---|---|
CD4 | CD8 | ||||
102 | 391 | 312 | 7.11 | Ia | 18 |
100 | 595 | 1,259 | 5.47 | II | 45 |
104 | 1,321 | 926 | 5.79 | II | 38 |
107 | 426 | 928 | 5.61 | Ia | 24 |
336 | 556 | 1,368 | 4.99 | II | 62 |
109 | 340 | 803 | 6.26 | II | 19 |
119 | 350 | 1,354 | 6.33 | Ia | 18 |
122 | 400 | 1,086 | 4.95 | III | 72 |
125 | 684 | 855 | 5.03 | II | 36 |
127 | 350 | 1,075 | 4.99 | Ia | 23 |
131 | 250 | 959 | 6.75 | Ia | 25 |
137 | 178 | 1,325 | 5.94 | Ia | 31 |
500 | 311 | 1,464 | 5.23 | Ia | 27 |
347 | 291 | 679 | 4.43 | Ia | 64 |
128 | 706 | 2,638 | 4.57 | Ia | 29 |
141 | 489 | 1,146 | 4.94 | III | 88 |
142 | 330 | 575 | 4.22 | II | NA |
143 | 442 | 621 | 5.17 | Ia | 28 |
351 | 956 | 1,017 | 3.42 | II | NA |
357 | 514 | 1,218 | 3.75 | III | NA |
146 | 391 | 633 | 4.52 | I | 51 |
147 | 194 | 267 | 5.97 | Ia | 30 |
502 | 408 | 3,011 | 7.46 | Ia | 19 |
503 | 631 | 607 | 5.66 | Ia | 18 |
508 | 176 | 2,116 | 5.74 | Ia | 26 |
148 | 332 | 754 | 5.40 | II | 87 |
512 | 820 | 1,598 | 6.51 | Ia | 38 |
368 | 346 | 1,070 | 4.62 | II | NA |
516 | 372 | 906 | 4.49 | II | 59 |
519 | 322 | 976 | 6.26 | Ia | 27 |
518 | 434 | 527 | 6.72 | Ia | 19 |
520 | 473 | 917 | 4.91 | Ia | 30 |
Mean | 462 | 1,093 | 5.41 | 37 |
Subjects were staged in accordance with the NIH-sponsored AIEDRP as follows: ELISA negative (stage Ia), Western blot indeterminate (stage Ib), nonreactive detuned ELISA result with an OD of <0.5 or a documented negative ELISA result within 3 months of presentation (stage II), and a nonreactive detuned ELISA result (OD of 0.51 to 1.0) or a documented negative serology within 6 months of presentation (stage III).
The estimated duration of infection was calculated 2 weeks prior to the onset of acute retroviral illness. In four subjects, the estimated duration of infection could not be calculated. Enrollment was based on nonreactive detuned ELISA result (stage II) or a documented negative HIV-1 test within the 6 months of biopsy (stage III). NA, not available.