FIG. 1.

Effects of vaccinia virus coinfection on VSV wt and VSV polR growth in BHK (A) and L-929 (B) cells. All infections were done at an effective MOI of 10 PFU/cell for both VSV and vaccinia (vac) in the presence of 2 μg/ml act D. Infectious VSV yields (left panels) and released virus particle amounts (right panels) were determined at ∼24 h (BHK) or ∼30 h (L-929) p.i. by plaque assay in BHK cells and Northern blot analysis of virus genomes. +, with vaccinia virus coinfection; −, without vaccinia virus coinfection.