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Inhibition of a promoter containing an ISRE by SARS-CoV proteins. 293T cells were cotransfected with ISRE-GFP and the indicated plasmid for 24 h. Cells were then infected with Sendai virus (A and B) or treated with IFN-β (C and D) for 24 h and then analyzed by microscopy using a 10× objective. Images were quantitated with ImageJ software (B and D). Data are averages plus standard deviations for three experiments.
