TABLE 4.
Long-term pp65-2 cellular responses postchallenge
Vaccinated group and monkey | Wk post-RhCMV challenge | % pp65-2-specific T lymphocytesa
|
|
---|---|---|---|
CD8+ | CD4+ | ||
I | |||
1 | 16 | 0.05 | 0.02 |
24 | 0.13 | 0.14 | |
2 | 16 | 0.13 | 0.02 |
24 | 0.05 | 0 | |
3 | 16 | 0.05 | 0.04 |
24 | 0.15 | 0.04 | |
4 | 16 | 0.01 | 0.02 |
24 | 0.04 | 0 | |
II | |||
5 | 16 | 0.53 | 0 |
24 | 0.30 | 0.03 | |
6 | 16 | 0.45 | 0.02 |
24 | 0.34 | 0.07 | |
7 | 16 | 0.06 | 0 |
24 | 0.18 | 0.05 | |
8 | 16 | 0.01 | 0 |
24 | 0.07 | 0.01 | |
Control | |||
9 | 16 | 0 | 0 |
24 | 0.03 | 0.01 | |
10 | 16 | 0 | 0 |
20 | 0 | 0.01 | |
11 | 16 | 0 | 0 |
20 | 0 | 0 | |
12 | 16 | 0.08 | 0.01 |
24 | 0 | 0 |
Frequency of CD8+ and CD4+ T lymphocytes responding to pp65-2 stimulation. Values are shown after subtraction of background with unstimulated PBMC. Values of >0.08% were considered positive.