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Enhanced influenza A virus replication in the lungs of IFN-β-deficient mice. Mx-wt and Mx-BKO mice were infected with either SC35M (5 × 104 PFU) (A) or PR8 (106 FFU) (B). At 72 h postinfection, the lungs were removed and the virus titers in lung homogenates were determined. Groups of six animals were analyzed. Mean values and standard deviations are displayed.
