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Antigen persistence does not occur following Listeria monocytogenes infection. CD45.2 B6 mice were inoculated with 1 × 104 CFU LM-Ova intranasally or 1 × 103 CFU LM-Ova intravenously, placed on ampicillin at day 7 after infection, and received naive CFSE-labeled CD45.1 OT-I cells at 10 or 22 days postinfection. Plots show the CFSE profiles of donor CD8+ CD45.1+ cells harvested 5 days after transfer. The numbers represent the percentages of Ova-specific donor cells that have divided.
