FIG. 3.

Growth kinetics of rVSV_IN mutants on Vero cell monolayers. Replicate Vero cell monolayers in 25 cm² flasks were infected in duplicate at an MOI of 5 PFU/cell. Infected-cell supernatants were collected at intervals postinfection and titrated on Vero cell monolayers. All datum points represent the average titers of samples taken from duplicate infections. Growth curves are shown for mutants containing N gene shuffles (A), CT truncations (B), N gene shuffle-CT truncation combinations (C and D), and M_NCP mutations (E).