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Antibody interactions with purified hexon and intact virus. (A) Purified hexon. Hexon (twofold serial dilutions) was immobilized and probed with MAbs. Nonneutralizing antibodies are labeled with an x and represented with dotted lines; neutralizing antibodies are shown with solid lines. (B) Intact virions. AdC68 purified by CsCl centrifugation was diluted, immobilized, and probed as performed for hexon. An IgG1 myeloma protein, MOPC21, was used as a nonspecific control.
