TABLE 2.
Inhibition of B. subtilis topoisomerase IV and gyrase
| Compound | IC50 (μM) for:
|
|
|---|---|---|
| Topoisomerase IV | Gyrase | |
| 251D | 43.6 | 31 |
| 340E | 4.2 | 5.6 |
| Ciprofloxacin | 1.7 | 6.3 |
| Nalidixic acid | 1,090 | 149 |
| HB-EMAU | >500 | >500 |
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