TABLE 3.
Antibacterial activity in vitro
| Organism | MIC (μg/ml) of:
|
||
|---|---|---|---|
| 251D | HB-EMAU | 340E | |
| Bacilli | |||
| B. subtilis BD54 | 0.156 | 1.25 | 0.039 |
| B. cereus 4342 | 0.156 | 1.25 | 0.078 |
| B. cereus 6464 | 0.156 | 1.25 | 0.078 |
| B. thuringiensis 10792 | 0.156 | 1.25 | 0.156 |
| B. thuringiensis 33679 | 0.156 | 2.5 | 0.078 |
| B. anthracis Sterne | 0.156 | 2.5 | 0.039 |
| Staphylococci | |||
| S. aureus 25923 | 0.625 | 5 | 0.156 |
| S. aureus (Smith) 13709 | 0.313 | 5 | 0.078 |
| S. aureus 1081 | 0.625 | 5 | 10 |
| MRSA 1094 | 1.25 | 5 | 20 |
| MRSA B42876 | 2.5 | 5 | 80 |
| MRSA 1123 | 1.25 | 5 | 20 |
| MRSA 1132 | 0.625 | 5 | 0.156 |
| S. aureus mupirocin-sensitive 2529 | 5 | 20 | 80 |
| S. aureus mupirocin-resistant 777 | 2.5 | 10 | 40 |
| Enterococci | |||
| E. faecalis 29212 | 1.25 | 5 | 0.313 |
| VREF 700802 | 1.25 | 5 | 0.313 |
| VREF 51575 | 1.25 | 5 | 0.313 |
| VREF 51299 | 1.25 | 5 | 0.313 |
| E. faecium 19434 | 2.5 | 5 | 10 |
| Vancomycin-resistant E. faecium B42762 | 1.25 | 5 | 40 |
| Vancomycin-resistant E. faecium 1644 | 1.25 | 2.5 | 40 |
| VREF F118 (linezolid resistant) | 1.25 | 10 | 80 |
| Streptococci | |||
| S. pneumoniae 49619 | 0.625 | 2.5 | 0.313 |
| PRSP 700670 (Spain) | 0.625 | 5 | 0.313 |
| PRSP 700674 (S. Africa) | 0.625 | 5 | 0.625 |
| PRSP 700671 (France) | 0.313 | 2.5 | 0.313 |
| PRSP 700673 (Hungary) | 0.313 | 2.5 | 0.156 |
| PRSP 700677 (Slovakia) | 0.313 | 2.5 | 0.625 |
| S. pyogenes 12344 | 0.313 | 1.25 | 0.156 |
| Gram-negative strains | |||
| E. coli J53 | 2.5 | >80 | 0.01 |
| E. coli XL1-Blue (ciprofloxacin resistant) | 1.25 | >80 | 40 |
| K. pneumoniae 5657 | 20 | >80 | 0.156 |
| S. maltophilia 13637 | 10 | >80 | 0.078 |
| P. aeruginosa 27853 | >80 | >80 | 0.313 |