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Effect on MICs of combining individual agents versus the linked hybrid
| Bacterial strain | MIC (μM) of:
|
Hybrid/combination ratio | |||
|---|---|---|---|---|---|
| 251D | HB-EMAU | 340E | HB-EMAU + 340E | ||
| S. aureus Smith ATCC 13709 | 0.88 | 28 | 0.26 | 0.88 | 1 |
| MRSA clinical isolate 1094 | 2.6 | 28 | 30 | 30 | 11.5 |
| E. faecium ATCC 19434 | 3.75 | 30 | 30 | 30 | 8.0 |
| VRE clinical isolate B42762 | 2.1 | 30 | >60 | 45 | 21.3 |
