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. 2006 Oct 23;51(1):169–174. doi: 10.1128/AAC.00261-06

TABLE 5.

MICs of antibiotics for hydrogen peroxide-stresseda bifidobacteria

Organism MIC (μg/ml)b of the following antibioticc for the indicated organism:
Amp Clo Pen Van Kan Neo Par Str Chl Ery Tet Nis
B. animalis ATCC 27536 3.9 3.9 0.98 >500 500 500 500 250 3.9 0.98 62.5 0.98
B. bifidum R 0071 0.98 31.2 0.98 >500 500 125 125 250 1.9 500 62.5 0.98
B. bifidum ATCC 15696 Did not survive H2O2 stressing
B. bifidum BB12 0.98 1.9 0.98 >500 500 250 500 250 1.9 0.98 7.8 0.98
B. breve ATCC 15700 3.9 3.9 0.98 >500 >500 250 500 500 1.9 0.98 31.2 0.98
B. breve R0070 0.98 15.6 0.98 >500 500 250 250 250 1.9 0.98 7.8 0.98
B. infantis ATCC 15697 Did not survive H2O2 stressing
B. longum ATCC 15707 0.98 0.98 0.98 >500 500 250 500 62.5 1.9 0.98 7.8 0.98
B. longum ATCC 15708 3.9 7.8 0.98 >500 500 250 250 500 3.9 0.98 31.2 0.98
B. longum R0175 1.9 31.2 0.98 >500 500 125 250 250 1.9 0.98 15.6 1.9
B. longum P/N 601377 0.98 31.2 0.98 >500 250 125 125 125 1.9 1.9 125 0.98
B. pseudolongum ATCC 25562 Did not survive H2O2 stressing
B. thermophilum ATCC 25866 3.9 7.8 0.98 >500 500 500 500 500 1.9 0.98 15.6 0.98
a

Organisms were exposed for 90 min to H2O2 at the MIC prior to 18 h of anaerobic growth in MRS broth, pH 6.5.

b

Median of four repetitions.

c

Amp, ampicillin; Clo, cloxacillin; Pen, penicillin G; Van, vancomycin; Kan, kanamycin; Neo, neomycin; Par, paromomycin; Str, streptomycin; Chl, chloramphenicol; Ery, erythromycin; Tet, tetracycline hydrochloride; Nis, nisin A.