Figure 2.

MCK-1-induced Ca²⁺ flux leads to tight adherence. (A) Percentage of PECs from mock-infected mice responding to MCK-1, with three independent experiments shown. (B) Percentage of PECs from RM427⁺-infected mice (48 h post-i.p. inoculation) responding to MCK-1 (gray bars), with results from five independent experiments shown. Percentage of PECs that were virus-infected based on β-galactosidase expression also is shown (black bars). The digital images shown in Fig. 1 of PECs from mock-infected mice are from experiment 2 (Exp. #2), and those from RM427⁺-infected mice are from experiment 4. (C). Induction of tight adherence by MCK-1. The percentage of total adherent PECs that were loosely attached and that fluxed in response to MCK-1 (gray bars) and the percentage that adhered tightly to glass after responding to MCK-1 (black bars) are shown. Data are from the five experiments shown in B.