TABLE 3.

Bivariate analysis of the relationship between clinical features and MDR P. aeruginosa^a

Clinical feature	MDR P. aeruginosa (n = 122)	No MDR P. aeruginosa (n = 229)	P value
Age of ≥61 yrb	93 (66.9)	104 (49.1)	0.001
Sex (male)	82 (67.2)	133 (58.1)	0.09
Admission for ≥72 h within 6-mo prior to culture	54 (44.3)	100 (43.7)	0.9
LOS prior to collection of ≥33 daysb	73 (59.8)	58 (25.1)	<0.001
ICU at onset	107 (87.7)	180 (78.6)	0.04
ICU LOS of ≥27 days prior to cultureb	73 (59.8)	55 (24.0)	<0.001
Mechanical ventilation at culture	109 (89.3)	172 (75.1)	0.001
Congestive heart failure	27 (22.1)	46 (20.1)	0.65
Diabetes mellitus	47 (38.5)	51 (22.3)	0.001
Chronic obstructive pulmonary disease	46 (37.7)	72 (31.4)	0.2
Hepatic dysfunction	5 (4.1)	15 (6.6)	0.35
Dialysis	26 (21.3)	18 (7.9)	<0.001
Decubitus ulcers	35 (28.7)	37 (16.2)	0.006
Prior antibiotic exposure
Carbapenem, ≥3 daysb	33 (27.0)	31 (13.4)	0.002
Fluoroquinolone, ≥4 daysb	33 (27.0)	30 (13.0)	0.001
Aminoglycoside, ≥5 daysb	39 (32.0)	36 (15.9)	<0.001
Cefepime, ≥9 daysb	19 (15.6)	11 (4.8)	0.001
Piperacillin-tazobactam, ≥12 daysb	41 (33.6)	37 (16.9)	<0.001

^aResistance to at least four drug classes. All data are presented as number (percentage) unless otherwise indicated.

^bCART-derived breakpoint.