TABLE 6.
Comparison of prior antipseudomonal antibiotic exposure and MDR P. aeruginosa among the 135 patients with a hospital LOS of <33 days prior to culture sample collection and no prior CART-derived antibiotic exposurea
| Prior antibiotic exposureb | MDR P. aeruginosa (n = 27) | No MDR P. aeruginosa (n = 108) | P value |
|---|---|---|---|
| Carbapenem, 1-3 days | 1 (3.7) | 12 (11.1) | 0.2 |
| Fluoroquinolone, 1-4 days | 4 (14.8) | 12 (11.1) | 0.6 |
| Aminoglycoside, 1-5 days | 8 (29.6) | 32 (29.6) | 1.0 |
| Cefepime, 1-9 days | 1 (3.7) | 17 (15.7) | 0.1 |
| Piperacillin-tazobactam, 1-12 days | 18 (66.7) | 55 (50.9) | 0.1 |
| No. of prior antibiotic exposures: | |||
| 0 | 5 (18.5) | 23 (21.3) | |
| 1 | 13 (48.1) | 46 (42.6) | |
| 2 | 8 (29.6) | 35 (32.4) | |
| 3 | 1 (3.7) | 4 (3.7) | 0.9 |
a
All data are presented as number (percentage) unless otherwise indicated.
b
Carbapenem exposure for 1 to 3 days, fluoroquinolone exposure for 1 to 4 days, aminoglycoside exposure for 1 to 5 days, cefepime exposure for 1 to 9 days, and piperacillin-tazobactam exposure for 1 to 12 days were defined as antibiotic exposures prior to culture sample collection.