TABLE 1.
Variations in bacterial counts of 90 isolates of CoNS after 6 and 24 h of glycopeptide exposition at 10× MIC
| Strain | Mean (SDa) Δlog CFU/ml forb:
|
|||
|---|---|---|---|---|
| Vancomycin
|
Teicoplanin
|
|||
| 6 h | 24 h | 6 h | 24 h | |
| First-set strains (n = 79) | ||||
| 77 CoNS | −2.98 (1.04) | −4.80 (0.98) | −3.22 (0.98) | −5.33 (0.74) |
| S. lugdunensis 111A53 | −0.31 (0.08) | −1.94 (0.18) | −0.66 (0.16) | −3.77 (0.23) |
| S. lugdunensis 111A91 | −0.31 (0.08) | −3.53 (0.20) | −0.34 (0.10) | −2.26 (0.16) |
| Additional-set strains (n = 11) | ||||
| 7 S. lugdunensis strains | −1.17 (0.74) | −4.10 (0.70) | −0.49 (0.26) | −4.42 (0.62) |
| S. lugdunensis ATCC 49576 | −1.38 (0.23) | −3.91 (0.17) | −0.47 (0.11) | −2.40 (0.33) |
| S. lugdunensis 111A223 | −0.67 (0.23) | −1.65 (0.24) | −0.43 (0.07) | −2.81 (0.11) |
| S. lugdunensis ATCC 43809 | −0.21 (0.16) | −2.18 (0.44) | −0.12 (0.06) | −1.29 (0.33) |
| S. lugdunensis 111A229 | −2.24 (0.47) | −2.42 (0.25) | −0.31 (0.21) | −2.33 (0.31) |
a
Experiments were performed in duplicate for each strain.
b
Boldface type indicates a tolerance phenomenon according to CLSI criteria.