FIG. 3.

Inhibition of recombinant PfGCN5 activity by curcumin. HAT assay was performed with rGCN5 in the presence or absence of curcumin using bovine core histones as substrates. DMSO was included as the solvent control. The IC₅₀ calculated from this experiment was ∼48 μM. The means plus standard deviations (error bars) from three replicate samples are shown.