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. 2006 Dec 4;51(2):667–672. doi: 10.1128/AAC.01064-06

FIG. 1.

FIG. 1.

RBX11160 inhibition of transporter activities. (a) Inhibition of PfATP6 activity by RBX11160 (50 μM) compared with results for control preparations (n = 6 for both groups; P = 0.0018). (b) Inhibition of mammalian SERCA by RBX11160 (100 μM; P = 0.13) and thapsigargin (10 μM; P = 0.0007) compared with results for control experiments. (c) Uptake of d-glucose in water-injected (diethyl pyrocarbonate [DEPC]) and PfHT-expressing oocytes is shown. There is no inhibition of PfHT activity by RBX11160 (50 μM, n ≥ 9 per column; P > 0.5). DMSO, dimethyl sulfoxide.