A schematic diagram of the tro operon from T. pallidum. (A) Shown is the relative position of the promoter (−10 and −35), the putative ribosome binding site (RBS), the 5′ end of the mRNA (+1), the putative translational start site (start), and the region protected from DNase I digestion by purified TroR (protected region). The nucleotide sequence of each region is shown below the designated site. (B) Comparison of the binding site of TroR to the consensus binding sequences of Fnr, Fur, and DtxR