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DNase I footprint analysis of the activation of TroR by divalent heavy metal ions. An autoradiograph of a 6% denaturing polyacrylamide gel showing the effect of different divalent metal ions on the binding of TroR to the target sequence. The metal used in each reaction (final concentration of 100 μM) is shown at the top. The lane designated − contained no metal. The region protected from DNase I digestion is shown to the right.
