Figure 1. Rearrangements between the Meningococcal Genomes.

The dotplots were generated using MUMmer version 3.15 (http://mummer.sourceforge.net) and indicate matching sequences with codirectional and reversed regions of synteny shown in red and green, respectively. Genome sequences are aligned to start/finish at the origin of replication with the approximate position of the terminus of replication indicated (Ter) (note this required rotation of the publicly available sequences for Z2491 and MC58, see Materials and Methods). Also shown are the positions of the foci of the three major inversion events (IE1, IE2, and IE3, see text for detail).