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. 2003 Aug;41(8):3526–3531. doi: 10.1128/JCM.41.8.3526-3531.2003

FIG. 5.

FIG. 5.

Position and frequency of exoY DNA and amino acid sequence variations (n = 9) and position of PCR primers and conserved regions between P. aeruginosa, B. pertussis, and B. anthracis adenylate cyclases. The x axis represents the nucleotide or amino acid position; the y axis represents the percentage of P. aeruginosa isolates that differed in sequence from PAO1 at each position. Two lysine residues (Lys-81 and Lys-88) in conserved region I and two arginine residues (Arg-212 and Arg-214) in conserved region II are essential for the adenylate cyclase activity of ExoY.