. Author manuscript; available in PMC: 2007 Dec 1.

Published in final edited form as: Virology. 2006 Sep 7;356(1-2):165–170. doi: 10.1016/j.virol.2006.08.006

Table 3.

Direct measurement of p24 concentrations.^a

	Apical Supernatant		Basal Medium		Cell Lysate
IgA MAb (150μg/mL)	p24 (ng/mL)	% Virus Reduction^b	p24 (ng/mL)	% Virus Reduction^b	p24 (ng/mL)	% Virus Reduction^b
Control	7.0 ± 0.9		7.7 ± 0.9		29.9 ± 4.0
Anti-RT	6.2 ± 1.4	11^c	6.3 ± 0.5	18^c	26.7 ± 4.2	11^c
Anti-Gag	6.3 ± 1.4	10^c	6.2 ± 1.7	19^c	26.7 ± 2.3	11^c

Experiments as in Table 1 except that p24 concentrations were measured. MAbs were added for 18 h to the basolateral surface of polarized monolayers of pIgR⁺ Vero C1008 cells that had been transfected with HIV proviral DNA for 4 h. HIV levels in apical supernatants, basolateral media and cell lysates 30 h post transfection were determined by p24 ELISA assay. Data are means from 11 data points ± SEM pooled from seven experiments.

Compared to the no antibody control.

Mean virus titer significantly less than control (p<0.02).