Table 1 Comparison of anti‐CCP Ab+ and anti‐CCP Ab− patients.

Variables	Anti‐CCP Ab+	Anti‐CCP Ab−	p Value
	(n = 54)	(n = 26)
CRP (mg/ml)	1.3 (2.0)	2.2 (3.3)	0.39*
MMP‐3 (%)	50.0	38.5	0.33†
Number of joints with synovitis	12.2 (6.4)	10.3 (6.4)	0.30*
Mean E‐rate of 30 joints	7.7 (3.0)	7.4 (2.9)	0.67*
Bone marrow oedema
%	64.8	38.5	0.03†
No	2.8 (3.5)	1.1 (2.3)	0.01*

Data are mean (SD) unless stated otherwise. The proportion of patients with bone marrow oedema was significantly higher in the anti‐CCP Ab+ group than in the anti‐CCP Ab‐ group: *by Mann‐Whitney U test; †by χ² test.