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. 2005 Jun 23;65(2):227–233. doi: 10.1136/ard.2005.038513

Table 4 Association of effect sizes of the Health Assessment Questionnaire with duration of rheumatoid arthritis (all treatment arms).

Models (R2)* Variable 3 month analysis 6 month analysis
Parameter estimate (95% CI) p Value Parameter estimate (95% CI) p Value
Adjusted for effect sizes of pain: n = 26 (3 months) and n = 47 (6 months)
Unweighted (R2 = 0.45/0.46) Pain (ES) 0.60 (0.31 to 0.89) <0.001 0.71 (0.48 to 0.95) <0.001
Duration (y) −0.01 (−0.04 to 0.03) 0.66 −0.02 (−0.05 to 0) 0.10
Weighted (R2 = 0.68/0.57) Pain (ES) 0.94 (0.65 to 1.23) <0.001 0.79 (0.57 to 1.00) <0.001
Duration (y) −0.02 (−0.06 to 0.01) 0.13 −0.03 (−0.05 to −0.01) <0.01
Adjusted for effect sizes of tender joint counts: n = 27 (3 months) and n = 41 (6 months)
Unweighted (R2 = 0.31/0.23) TJC (ES) 0.46 (0.17 to 0.75) <0.01 0.39 (0.14 to 0.63) <0.01
Duration (y) −0.01 (−0.03 to 0.02) 0.63 −0.01 (−0.04 to 0.01) 0.33
Weighted (R2 = 0.53/0.32) TJC (ES) 0.67 (0.39 to 0.95) <0.001 0.45 (0.21 to 0.69) <0.001
Duration (y) −0.02 (−0.04 to −0.01) <0.01 −0.02 (−0.04 to −0.01) 0.01

*R2 values are given for the 3 months/6 months model.

CI, confidence interval; ES, effect size; TJC, tender joint count; y, years.