Figure 2 Effect of rAAV2hVIP and rAAV2LacZ on salivary flow rate in NOD mice. Mice were anaesthetised and pilocarpine stimulated whole saliva was collected, as described in “Materials and methods”. Salivary flow rate (μl/body weight (grams) in 20 minutes) at 8 weeks (n = 19; randomly selected from both groups, untreated) and mice at 16 weeks of age either treated with rAAV2LacZ (LacZ, n = 13) or rAAV2hVIP (hVIP, n = 15) is shown. Bars represent means (SEM). Student's t tests were performed and the p values for the differences are indicated.