Table 2 Genotype, carrier, and allele frequencies of IL4 −590, IL13 +2044, and IFNG +874 in 63 patients with primary Sjögren's syndrome and 63 healthy control subjects.
Genotype | pSS patients | Control subjects | p Value |
---|---|---|---|
IL4 −590 genotypes | |||
CC | 26 (41) | 32 (51) | |
CT | 31 (49) | 26 (41) | |
TT | 6 (10) | 5 (8) | 0.563 |
T allele carrier | 37 (59) | 31 (49) | 0.284 |
Allele frequencies | |||
Allele C | 0.659 | 0.714 | |
Allele T | 0.341 | 0.286 | 0.342 |
IL13 +2044 genotypes (n = 59) | |||
GG | 24 (41) | 28 (45) | |
AG | 30 (51) | 31 (49) | |
AA | 5 (8) | 4 (6) | 0.859 |
A allele carrier | 35 (59) | 35 (56) | 0.674 |
Allele frequencies | |||
Allele A | 0.339 | 0.310 | |
Allele G | 0.661 | 0.690 | 0.623 |
IFNG +874 genotypes | |||
AA | 27 (43) | 23 (37) | |
AT | 28 (44) | 31 (49) | |
TT | 8 (13) | 9 (14) | 0.767 |
T allele carrier | 8 (13) | 9 (14) | 0.794 |
Allele frequencies | |||
Allele A | 0.651 | 0.611 | |
Allele T | 0.349 | 0.389 | 0.269 |
Statistical analysis by χ2 test.
IFNG, interferon γ gene; IL, interleukin; pSS, primary Sjögren's syndrome.