Table 3 Incidence of lymphoma in RA patients29,30,31,32.
Study | Country | No. of patients with RA | Years of follow up, mean (max) | SIR for cancer | SIR for lymphoma (odds ratio/RA activity level) |
---|---|---|---|---|---|
Gridley et al29 | Sweden | 11 683 | 8.6 (20) | 1.0 | 2.0 |
Mellemkjaer et al30 | Denmark | 20 699 | 7 (15) | 1.1 | 2.5 |
Isomaki et al31 | Finland | 46 101 | 4.6 (7) | 1.1 | 2.7 |
Adalimumab 2005 | Global | 10 024* | 1.2 (7.7) | 1.06 | 3.19 |
1.0 (low) | |||||
Baecklund et al32 | Sweden | 11 683 | 8.6 (20) | – | 5.4 (medium) |
25.8 (high) |
*As of 15 April 2005.