Table 1.

Mean (± SEM) percentage of total time in each sleep stage determined during the second and third hour postdose using area under the curve calculations

Sleep stage	Control	10.0 (μg/rat ICV), n = 9
Arousal	13.4  ±  4.9%	34.5  ±  8.7%*
Paradoxical sleep	5.9  ±  1.8%	1.9  ±  0.9%†
SWS1	13.1  ±  1.8%	13.0  ±  2.9%;  NS
SWS2	67.6  ±  5.9%	50.7  ±  8.2%;  NS

NS, nonsignificant. SWS, slow wave sleep. 

^*Increased relative to vehicle, P < 0.05. 

^†Decreased relative to vehicle, P < 0.05.