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. 1999 Sep 14;96(19):10911–10916. doi: 10.1073/pnas.96.19.10911

Table 2.

Effects of orexin A on neuroendocrine markers

Markers Dose of orexin A (μg/rat ICV)
Control 0.3 1.0 3.0 10.0 30.0
Prolactin, ng/ml 4.84  ±  1.4 1.08  ±  0.86* ND < 0.1* ND < 0.1* ND < 0.1* ND < 0.1*
Growth hormone, ng/ml 29.8  ±  12.5 37.9  ±  8.98 9.6  ±  2.9* 3.8  ±  0.95* 3.5  ±  1.09* 1.7  ±  0.29*
Corticosterone, ng/ml 44.0  ±  8.99 38.8  ±  5.7 74.6  ±  13.02 60.3  ±  14.7 104.2  ±  24.8* 140.5  ±  21.1*
Thyroid-stimulating hormone, ng/ml 6.8  ±  1.74 7.9  ±  0.95 6.6  ±  0.71 6.1  ±  1.30 7.6  ±  1.32 NA

 NA, experiment not done; ND, below limit of detection. ∗, P < 0.05 c.f. vehicle.