Table 1 Main clinical, serological, and histopathological features of Sjögren's syndrome associated lymphoma at diagnosis.
| Case 1† | Case 2† | Case 3† | Case 4 | Case 5 | Case 6† | |
|---|---|---|---|---|---|---|
| Age (y) | 62 | 37 | 51 | 45 | 74 | 54 |
| Type of lymphoma | Diffuse large B cell | Nodal marginal zone | Diffuse large B cell | Nodal marginal zone | Diffuse large B cell | Diffuse large B cell |
| Ann Arbor stage | IV | II | IV | II | II | IV |
| Performance status | 0 | 0 | 0 | 0 | 1 | 0 |
| B symptoms | − | + | − | − | − | + |
| Lymphadenopathy | + | + | − | + | + | + |
| Splenomegaly | + | − | − | − | + | + |
| β2‐Microglobulin (mg/l)* | 8.9 | 5 | 8.2 | 12 | 4.6 | 7.4 |
| Serum LDH level (U/l)‡ | 670 | 520 | 938 | 250 | 520 | 750 |
| Extranodal involvement | Salivary glands | Salivary glands | Lung, salivary glands | − | − | Salivary glands |
| Bone marrow involvement | + | − | + | − | − | + |
| IPI score | 4 | 1 | 3 | 0 | 2 | 3 |
*Increased β2‐microglobulin >3 mg/l.
†Previously reported cases.
‡Normal lactate dehydrogenase level: 200–475 U/l.
IPI, international prognostic index; y, years.