Table 2 Three month biochemical marker levels.
| Variable | Median (range) |
|---|---|
| Serum hyaluronic acid (ng/ml) | 68 (19 to 293) |
| Serum osteocalcin (ng/ml) | 12.6 (5.2 to 31.3) |
| Serum COMP (ng/ml) | 1711 (931 to 2784) |
| Serum YKL‐40 (ng/ml) | 77 (24 to 439) |
| Serum CTX‐I (pM) | 3112 (997 to 9688) |
| Urine CTX‐II (μg/mmol creatinine) | 0.27 (0.09 to 0.85) |
COMP, cartilage oligomeric matrix protein; CTX‐I, C‐telopeptides of type I collagen; CTX‐II, C‐telopeptides of type II collagen; YKL‐40, cartilage glycoprotein 39.