Table 5 Cumulative exposure adjusted event rates for the most frequent serious infections (n ⩾2) by preferred term after three years of anakinra exposure (without steroid use at baseline v with steroid use at baseline).

Without corticosteroid use at baseline			With corticosteroid use at baseline
(n = 569) (E = 940.3)			(n = 777) (E = 1332.7)
Preferred term	n	EAE rate*	Preferred term	n	EAE rate*
Any	27	2.87	Any	95	7.13
Pneumonia	9	0.96	Pneumonia	20	1.50
Cellulitis	2	0.21	Cellulitis	16	1.20
Diverticulitis	2	0.21	Infection	9	0.68
Lower respiratory infection	2	0.21	Sepsis	5	0.38
			Abscess abdomen	3	0.23
			Bronchitis	3	0.23
			Infection bacterial	3	0.23
			Osteomyelitis	3	0.23
			Pneumonia lobar	3	0.23
			Gastroenteritis	2	0.15
			Pneumonia bacterial	2	0.15
			Pyelonephritis	2	0.15
			Upper respiratory infection	2	0.15

*Number of events per 100 patient‐years.

E, number of patient‐years of exposure; EAE, exposure adjusted event.