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Time course of whole-cell currents from a T cell activated by purified protein derivative (PPD) at −80 mV measured from voltage ramps (±100 mV every 5 s, 200-ms duration) under control conditions (extracellular K+ solution in the bath) and during the application of the indicated compounds. The concentrations used were ketoconazole (Keto), 1 μM; nitrendipine (Nitr), 1 μM; charybdotoxin (ChTx), 200 nM; and clotrimazole (CLT), 1 μM. Free Ca2+ in the pipette solutions was 1 μM.
