Table 4 Genotypic and allelic distribution of NFκB1 insertion or deletion in patients with rheumatoid arthritis and in controls.
n | Del/del | Del/ins | Ins/ins | Alleles | Del | Ins | |
---|---|---|---|---|---|---|---|
Controls from Madrid | 458 | 74 (16) | 214 (47) | 168 (37) | 916 | 362 (40) | 554 (60) |
Controls from Granada | 247 | 35 (14) | 107 (43) | 105 (43) | 494 | 177 (36) | 317 (64) |
Patients from Madrid | 376 | 61 (16) | 168 (45) | 147 (39) | 752 | 290 (39) | 462 (61) |
Patients from Granada | 245 | 28 (11) | 124 (51) | 93 (38) | 490 | 180 (37) | 310 (63) |
del, deletions; ins, insertions; NFκB1, nuclear factor κB1; RA, rheumatoid arthritis.
Values in parentheses are percentages.
Overall genotype comparison (Madrid and Granada), p = 0.80.
Minimum detectable allelic RR = 1.25.