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. 2006 Apr 27;65(10):1373–1378. doi: 10.1136/ard.2006.051706

Table 4 Discriminative capacity of response criteria.

IMPACT Placebo (n = 52) Active drug (n = 52) χ2MH p Value
Response criteria % improved % improved
EULAR28 53.4 <0.001
 Good+moderate 26 92%
 Good 0 60
EULAR 48.6 <0.001
 Good+moderate 26 88
 Good 0 63
ACR20 10 67 36.2 <0.001
ACR50 0 48 32.6 <0.001
ACR70 0 29 17.4 <0.001
PsARC 30 82 27.9 <0.001
ΔDAS28>1.2 13 83 49.4 <0.001
ΔDAS>1.2 10 67 36.2 <0.001
Low‐disease activity criteria % reached % reached χ2MH p Value
DAS28⩽3.2 4 61 35.3 <0.001
DAS⩽2.4 8 65 33.4 <0.001
OMERACT MDAS 6 50 25.1 <0.001
DAS28⩽2.6 2 41 21.2 <0.001
DAS⩽1.6 0 35 20.0 <0.001
Etanercept Placebo (n = 30) Active drug (n = 30) χ2MH p Value
Response criteria % improved % improved
EULAR28 26.2 <0.001
 Good+moderate 15 93
 Good 8 59
EULAR 24.1 <0.001
 Good+moderate 19 89
 Good 4 44
ACR20 15 73 19.6 <0.001
ACR50 4 50 14.8 0.001
ACR70 0 13 3.8 0.05
PsARC 33 90 19.3 <0.001
ΔDAS28>1.2 7 80 32.2 <0.001
ΔDAS>1.2 7 60 18.9 <0.001
Low‐disease activity criteria % reached % reached χ2MH p Value
DAS28⩽3.2 11 69 19.0 <0.001
DAS⩽2.4 15 69 16.4 <0.001
OMERACT MDAS 7 63 20.8 <0.001
DAS28⩽2.6 11 59 13.5 0.002
DAS⩽1.6 4 45 12.4 0.004

ACR, American College of Rheumatology; DAS, Disease Activity Score; EULAR, European League Against Rheumatism; IMPACT, Infliximab Multinational Psoriatic Arthritis Controlled Trial; MDAS, minimal disease activity in rheumatoid arthritis; OMERACT, Outcome Measures in Rheumatoid Arthritis Clinical Trials; PsARC, psoriatic arthritis response criteria; χ2MH, χ2 Mantel Haenszel.