Table 2 Fractions of IgG‐positive and IgG‐negative B cells that are positive for RAG genes.
Healthy | o‐JIA | |||
---|---|---|---|---|
IgG pos | IgG neg | IgG pos | IgG neg | |
CD19+ CD27+ CD5+ (n) | 19 | 207 | 16 | 168 |
RAG1 (%) | 11 | 11 | 13 | 18 |
RAG2 (%) | 32 | 29 | 0 | 7 |
RAG1+RAG2 (%) | 0 | 1 | 0 | 2 |
CD19+CD27+CD5− (n) | 43 | 140 | 66 | 118 |
RAG1 (%) | 30 (p<0.01) | 11 | 23 | 22 |
RAG2 (%) | 33 | 27 | 14 | 11 |
RAG1+RAG2 (%) | 9 | 4 | 0 | 0 |
Ig, immunoglobulin, neg, negative; o‐JIA, oligoarticular juvenile idiopathic arthritis; pos, positive; RAG, recombination‐activating gene.