TABLE 5.
Antigen recognition at selected time pointsa
| Protein | No. of animals recognized (n = 6)
|
|||||
|---|---|---|---|---|---|---|
| Early
|
Middle
|
Late
|
||||
| Low | High | Low | High | Low | High | |
| TB10.4 | 4 | 4 | 0 | 2 | 2 | 2 |
| TB15.8 | 0 | 1 | 2 | 0 | 2 | 0 |
| TB16.2 | 5 | 2 | 2 | 2 | 2 | 2 |
| TB27.4 | 3 | 4 | 5 | 6 | 2 | 3 |
| CFP10 | 5 | 6 | 5 | 5 | 3 | 5 |
| ESAT6 | 5 | 5 | 5 | 5 | 4 | 5 |
| PPDB | 5 | 6 | 6 | 6 | 6 | 6 |
a
Number of animals recognized by single antigens at three different time points, and two infective doses. Six animals were tested in each group. For the group infected with 104 CFU of M. bovis (low), the number of animals recognized is shown at 20, 91, and 203 days postinfection, corresponding to early, middle, and late, respectively. For the group infected with 106 CFU of M. bovis (high), results are shown for 21, 98, and 180 days postinfection.