Table 2 Cumulative clinical features of patients from the LUpus in MInority: Nature vs. Nurture cohort, according to their work disability status.
| Feature | Work disability | p Value* | |
|---|---|---|---|
| Yes n = 39 | No n = 234 | ||
| Total disease duration, years, mean (SD) | 5.8 (3.9) | 4.4 (3.0) | 0.047 |
| Organ‐system involvement, % | |||
| Integument | 33 | 62 | 0.001 |
| Musculoskeletal | 36 | 71 | <0.001 |
| Serosal | 15 | 20 | |
| Pulmonary | 3 | 5 | |
| Neurological | 5 | 3 | |
| Renal | 69 | 39 | <0.001 |
| Haematological | 15 | 52 | <0.001 |
| Average SLAM‐R score, mean (SD) | 12.9 (5.5) | 8.0 (3.7) | <0.001 |
| Patient's global assessment, mean (SD) | 4.5 (3.4) | 3.2 (2.8) | 0.030 |
| Physician's global assessment, mean (SD) | 3.6 (2.6) | 1.9 (1.8) | <0.001 |
| SDI score, mean (SD) | |||
| At enrolment | 1.3 (1.8) | 0.3 (0.7) | <0.001 |
| At last visit | 2.5 (2.6) | 0.7 (1.5) | <0.001 |
| Comorbidities, % | |||
| Diabetes mellitus | 0 | 2 | |
| Hypertension | 54 | 44 | |
| Body mass index | 26.9 (5.2) | 26.6 (5.4) | |
| Congestive heart failure | 10 | 7 | |
| Myocardial infarction | 0 | 8 | 0.086 |
| Avascular osteonecrosis | 5 | 1 | 0.099 |
| Fibromyalgia | 0 | 7 | |
| Depression | 5 | 23 | 0.009 |
| Cognitive impairment | 0 | 6 | |
| Pain (0–10 cm VAS), mean (SD) | 4.0 (2.4) | 3.1 (2.4) | 0.036 |
SDI, Systemic Lupus International Collaborating Clinics Damage Index; SLAM‐R, Systemic Lupus Activity Measure—Revised; VAS, Visual Analogue Scale
*Only p⩽0.10 are recorded.