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. 2007 Feb 12;402(Pt 2):387–395. doi: 10.1042/BJ20061096

Figure 6. LPS-induced increase in resistin mRNA and promoter activity were inhibited by LY294002.

Figure 6

Untransfected (A) or pResistin(−996/+61)-Luc-transfected (B) RAW264.7 cells were pre-treated for 30 min with LY294002 (50 μM), then treated with 10 ng/ml LPS for 4 h. Resistin mRNA and luciferase activities were assayed as described. Fold activation (+LPS/−LPS) of luciferase activity by LPS treatment is shown. Results are means±S.D. for three independent experiments. *P<0.05 compared with that without pre-treatment with LY294002.