Table 2 Results of semiquantitative scoring for STAT1, STAT4, STAT6 and Jak3 expression in synovial tissue of rheumatoid arthritis patients before and after disease‐modifying antirheumatic drug treatment.

		Median SQA STAT1 (range)	Median SQA STAT4 (range)	Median SQA STAT6 (range)	Median SQA Jak3 (range)
Responders (n = 11) Before DMARD treatment	Lining	4 (1–4)	0 (0–1)	3 (0–4)	0 (0–2)
	Sublining	2 (0–4)	0 (0–2)	2 (0–4)	0 (0–3)
Responders (n = 11) After DMARD treatment	Lining	1 (0–3)*	0 (0)	2 (0–4)	0 (0)
	Sublining	0 (0–3)*	0 (0)	0 (0–3)*	0 (0)
Non‐responders (n = 5) Before DMARD treatment	Lining	3 (1–4)	1 (1–2)	2 (1–3)	0 (0–2)
	Sublining	2 (1–3)	1 (1–2)	1 (1–2)	0 (0–2)
Non‐responders (n = 5) After DMARD treatment	Lining	2 (1–2)	1 (1–2)	1 (1–2)	0 (0–2)
	Sublining	2 (1–3)	2 (1–2)	2 (1–2)	0 (0–1)

DMARD, disease‐modifying antirheumatic drug; SQA, semi‐quantitative analysis; STAT, signal transducer and activator of transcription.

Responders, patients who have had a significant clinical response to DMARD treatment; Non‐responders, patients who have not had a significant clinical response to DMARD treatment.

*p<0.05 compared with baseline biopsy.