Figure 2 In the American College of Rheumatology (ACR)50% and the non‐responder groups of patients with rheumatoid arthritis, increased density of CC chemokine receptor 2 (CCR2) is seen on monocytes at week 0 (p<0.001). The expression in the ACR50% responder group was increased compared with the non‐responders and decreased significantly as a result of treatment with methotrexate (p = 0.019). Median values marked by horizontal lines. PE, phycoerythin.