Table 2 Genotype and allele distributions of the three vascular endothelial growth factor polymorphisms for the patients with systemic sclerosis and controls.
| Patients, n (%) | Controls (n = 249) | Patients with SSc (n = 416) | χ2 test |
|---|---|---|---|
| 634C/G | GG: 97/249 (38.9) | GG: 168/416 (40.4) | NS |
| GC: 115/249 (46.2) | GC: 181/416 (43.5) | NS | |
| CC: 37/249 (14.9) | CC: 67/416 (16.1) | NS | |
| Allele C: 189/498 (38.0) | Allele C: 315/832 (37.9) | NS | |
| 936 C/T | CC: 174/249 (69.9) | CC: 288/416 (69.2) | NS |
| CT: 71/249 (28.5) | CT: 121/416 (29.1) | NS | |
| TT: 4/249 (1.6) | TT: 7/416 (1.7) | NS | |
| Allele T: 79/498 (15.9) | Allele T: 135/832 (16.2) | NS | |
| 18‐bp insertion/deletion | II: 56/249 (22.5) | II: 85/416 (20.4) | NS |
| ID: 111/249 (44.6) | ID: 202/416 (48.6) | NS | |
| DD: 82/249 (32.9) | DD: 129/416 (31.0) | NS | |
| Allele D: 275/498 (55.2) | Allele D: 460/832 (55.3) | NS |
SSc, systemic sclerosis.