Table 1 Patient's characteristics before autologous haematopoietic stem cell transplantation.
Patient | Diagnosis | Age, sex | Organs involved, laboratory values, examinations | Treatment before HSCT | Months since diagnosis |
---|---|---|---|---|---|
1 | Undifferentiated vasculitis | 41, f | Kidney, active sediment, eye | Cyc, IV immunoglobulins | 42 |
2 | Behçet's disease | 49, m | CNS involvement, fever, posterior uveitis | Cyc, steroids | 84 |
3 | Behçet's disease | 32, m | Intracardial thrombus, pulmonalarterial aneurysma, polyarthritis | Cyc, MTX, steroids | 63 |
4 | Wegener's granulomatosis | 46, f | Eye, nose, ANCA neg | Cyc | 40 |
5 | Wegener's granulomatosis | 34, f | Lungs, sinus, kidney, c‐ANCA 1:320 | Cyc 100 g, CSA, kidney transplantation | 132 |
6 | Cryoglobulinaemia | 42, f | Skin vasculitis with ulcers, arthritis, cryoglobulins 5.9 mg/ml | Chlorambucil | 36 |
7 | Cryoglobulinaemia | 57, m | Arthritis, polyneuropathy | aPBSCT 2 years earlier, data lost | 33 |
8 | Cryoglobulinaemia | 30, m | GN, severe pulmonary hypertension, sys pap >60 mm Hg | Plasmapheresis, Cyc 18 g | 41 |
9 | Churg–Strauss angiitis | 31, f | Kidney, lung, LN, eosinophils 2200/μl, ANCA neg | Cyc 10 g, INF, CSA, AZA, MTX | 84 |
10 | Takayasu arteritis | 22, f | Aortitis (PET), ESR 75 mm/h | Cyc 2 g, infliximab, anakinra, MTX | 40 |
11 | Polychondritis | 36, f | Aortitis, scleritis, cartilages, ESR 100 mm/h | Infliximab, Cyc 13 g, fludarabine rapamycin, MMF | 114 |
12 | Polyarteritis nodosa | 41, m | Skin, heart, brain, kidney, ESR 60 mm/h | Cyc >100 g | 60 |
ANCA, antineutrophil cytoplasmic antibody; aPBSCT, autologous peripheral blood stem cell transplantation; AZA, azathioprine; c‐ANCA, classical antineutrophil cytoplasmic antibody substitute circulating with classical; CNS, central nervous system; CSA, ciclosporin A; Cyc, cyclophosphamide; ESR, erythrocyte sedimentation rate; f, female; GN, glomerulonephritis; HSCT, haematopoietic stem cell transplantation; INF, interferon; IV, intravenous; LN, lymph nodes; m, male; MTX, methotrexate; neg, negative; PET, positron emission tomography; sys pap, systolic pulmonary arterial pressure.