Table 1.
Agar dilution MIC values of nanoparticle emulsions NP0-4 (1% w/w drug in the emulsion) and beta-lactam monomers 1-4 against S. aureus (ATCC 25923) and MRSA (ATCC 43300).
| Sample | S. aureus | MRSA |
|---|---|---|
| Nanoparticles | ||
| NP0 | >256 | >256 |
| NP1 | 32 | 32 |
| NP2 | 16 | 16 |
| NP3 | 8 | 8 |
| NP4 | 16 | 16 |
| Lactam monomers | ||
| 1 | 128 | 128 |
| 2 | 128 | 128 |
| 3 | 64 | 64 |
| 4 | 128 | 128 |
MIC values refer to the lowest concentration of bound drug (μg/mL) needed to completely inhibit bacterial growth for 24 hours. MIC determinations were run in triplicate and the values obtained for each compound were invariant.