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. 1971 Jul 3;3(5765):18–22. doi: 10.1136/bmj.3.5765.18

Post-halothane Jaundice in Relation to Previous Administration of Halothane

William W Mushin, M Rosen, E V Jones
PMCID: PMC1800080  PMID: 5091889

Abstract

The time interval since previous anaesthesia was compared in a surgical population in South Wales and in patients who developed jaundice after halothane. There was a significant difference in the pattern of time interval since previous general anaesthetics in the surgical population and in those patients who developed jaundice after halothane. In the group who developed jaundice there was an “excess” of patients who had had a previous halothane anaesthetic within four weeks. Halothane should if possible be avoided in patients who have had it before, particularly if this was within the previous four weeks. In the case of repeat halothane anaesthetics within four weeks, the risk seems to lie between 1 in 6,000 and 1 in 22,000.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. MUSHIN W. W., ROSEN M., BOWEN D. J., CAMPBELL H. HALOTHANE AND LIVER DYSFUNCTION: A RETROSPECTIVE STUDY. Br Med J. 1964 Aug 8;2(5405):329–341. doi: 10.1136/bmj.2.5405.329. [DOI] [PMC free article] [PubMed] [Google Scholar]
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