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. Author manuscript; available in PMC: 2007 Feb 16.
Published in final edited form as: J Allergy Clin Immunol. 2006 Jul;118(1):257–268. doi: 10.1016/j.jaci.2006.04.039

FIG 6.

FIG 6

Gene profile analysis of the colon in the absence of RELM-β. A, Microarray analysis of the transcripts expressed in colonic samples. RNA from each mouse was subjected to chip analysis with Affymetrix mouse Genome MOE430_2 GeneChips. The RELM-β-/- group is composed of 5 mice, and the WT group is composed of 6 mice. The 32 genes differentially expressed (2-fold cut off and P < .05) in the RELM-β-/- mice compared with the WT mice have been ordered (fold change); upregulated genes are shown in red, and downregulated genes are shown in blue. The magnitude of the gene changes is proportional to the darkness of the color. Each column represents an individual mouse, and each line represents a separate gene. B, Quantitative analysis of REG3β and REG3γ expression levels in the colons of WT and RELM-β-/- mice using Affymetrix mouse Genome U430 Plus 2.0 GeneChips. C and D, Quantitative analysis of REG3β (Fig 6, C) and REG3γ (Fig 6, D) mRNA levels in the colons of WT and RELM-β-/- mice by using real-time PCR analysis. REG3 expression was normalized to GADPH expression in each individual sample. Results are expressed as fold change over WT mice. The black line represents the mean value in each group.